Needs

Expert-Source Solutions to Problems or Challenges

  1. [InnoCentive] Comparative Effectiveness Research and Precision Medicine Approaches for Heart Disease & Stroke Treatment

    Challenges | Contests
    Earlier this year, the American Heart Association (AHA), in partnership with Patient-Centered Outcomes Research Institute (PCORI), conducted a Challenge to hear patients' insights on how health decisions related to heart disease and stroke were made. After patients identified many areas of uncertainty, we are now turning to researchers and clinicians to address several of them through refinement i
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    Reward:
    $20,000 USD
  2. [InnoCentive] AstraZeneca Challenge: Determination of Free Drug Concentration in Lung

    Challenges | Contests
    The pharmacological effect of inhaled drugs normally correlates with the free drug concentration in the lung tissue. However, accurately determining the free drug concentration of drugs in the relevant lung tissues poses a great challenge to the scientific community. Current methods are rather limited and do not provide the required accuracy that would lead to a sound understanding of drug behavio
    0/5, 0 ratings
    Reward:
    $25,000 USD
  3. [InnoCentive] Alternatives to Live Vaccines

    Challenges | Contests
    Vaccination is a safe and effective way of gaining protection from preventable diseases. In order to elicit a natural immune response, some vaccines are prepared with live organisms. However, live vaccines are not recommended when the immune system is weakened or compromised. Therefore, the Seeker is searching for viable alternatives to live vaccines. This Theoretical Challenge requires only a wr
    0/5, 0 ratings
    Reward:
    $20,000 USD
  4. [InnoCentive] Preventing Rodent Burrows in Earthen Embankments

    Challenges | Contests
    The Bureau of Reclamation, in collaboration with the U.S. Army Corps of Engineers, State of Colorado Department of Natural Resources Dam Safety Branch, and various water irrigation districts that operate federal canals, is seeking new ideas for cost-effective ways to prevent rodents from burrowing into the earthen embankments of dams, canals, and levees. These burrows cause seepage paths in the em
    0/5, 0 ratings
    Reward:
    $20,000 USD
  5. [InnoCentive] AstraZeneca Challenge: In Vitro System to Assess Gastrointestinal Toxicity

    Challenges | Contests
    The gastrointestinal (GI) tract is the system of organs by which food is ingested and digested, nutrients are absorbed, and waste products are eliminated. GI cell proliferation is essential for maintaining normal physiological function and integrity of the protective epithelial barrier, however, as many GI cells turn over at a rapid rate, normal function and barrier maintenance are highly sensitiv
    0/5, 0 ratings
    Reward:
    $25,000 USD
  6. [InnoCentive]Improving Adherence for Obstructive Sleep Apnea Treatment

    Challenges | Contests
    Obstructive Sleep Apnea (OSA) affects millions of individuals in the United States and many more worldwide. Fortunately, an effective non-surgical treatment exists in the form of a continuous positive airway pressure (CPAP) device used while sleeping. Unfortunately, adherence to the use of a CPAP for people diagnosed with OSA lies in the 40-50% range despite past efforts to improve devices and edu
    0/5, 0 ratings
    Reward:
    $10,000 USD
  7. [innocentive] Disruptive 5G Device and/or Service

    Challenges | Contests
    The next generation of mobile data connectivity is just around the corner with 5G technology expected to be in use by 2020. 5G connectivity is expected to greatly enhance performance compared to existing 4G systems with improvements of at least a factor of 10 for data rates, latency, and number of simultaneous connections as well enhanced mobility. The Seeker is looking for new ideas for features,
    0/5, 0 ratings
    Reward:
    $20,000 USD
  8. [NineSigma] Enriching Air Liquide Scientific Territory

    Challenges | Contests
    Air Liquide produces high added value molecules and develops cutting edge technologies and services for its customers and patients. Essential Small Molecules such as O2, N2, H2, and CO2 embody the Air Liquide scientific territory
    0/5, 0 ratings
    Reward:
    3 cash prizes of €50,000 each
  9. [NineSigma] GE's Water & Process Technologies

    Challenges | Contests
    GE's Water & Process Technologies uses advanced technologies to solve the world's complex challenges related to water availability and quality, increased productivity, cost reduction, and environmental regulations.
    0/5, 0 ratings
  10. [NineSigma] Waste Heat Recovery from the Top of a Crude Oil Distillation Column

    Challenges | Contests
    NineSigma, representing PKN ORLEN, seeks submissions for waste heat recovery technologies that can operate with low-grade heat of about 115 to 120°C. The successful solution will address specifically the heat lost from the top of the K1 distillation column located in Orlen’s Plock refinery (Poland). For a full explanation of the contest, and to see a detailed description of the system, please view
    0/5, 0 ratings
    Reward:
    Closed
  11. [NineSigma] The Hershey Company: Cool Ship Technologies

    Challenges | Contests
    NineSigma, representing The Hershey Company, seeks to identify new systems or materials that will allow chocolate to be shipped in warm weather without the need for gel packs. For a full explanation of the contest, please view the Contest Summary Document.
    0/5, 0 ratings
    Reward:
    US$25,000
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  13. [NineSigma] Seeking Simulation of Self Pierce Riveting

    Needs | Expertise
    IncWell's partner is seeking technology capable of simulating the stresses and strains associated with a complete vehicle structure which contains self piercing rivets.
    0/5, 0 ratings
  14. [NineSigma] Surface Treatments with Prolonged Antimicrobial Activity

    Needs | Expertise
    Sealed Air seeks ingredients or delivery methods that allow treated surfaces to have prolonged antimicrobial activity (greater than 24 hrs).
    0/5, 0 ratings
  15. [NineSigma] Refrigerator Based Modules for the Removal of Pesticides from Fruit and Vegetables

    Needs | Expertise
    Haier seeks partners with technologies or methods to rapidly detect pesticides levels on the surface of fruit and vegetables.
    0/5, 0 ratings
  16. [NineSigma] Odor Elimination Technologies for Refrigerators

    Needs | Expertise
    Haier seeks partners with high-efficiency technologies or methods to eliminate odors from air within a refrigerator.
    0/5, 0 ratings
  17. [NineSigma] Automotive Interior Surfaces that Resist or Hide Dirt, Dust, and Oil

    Needs | Expertise
    Yanfeng Automotive seeks interior surfaces that have the ability to resist dirt/dust/debris and oil accumulation. The interior surface must always appear to be clean AND must appear to be easy to clean.
    0/5, 0 ratings
  18. [NineSigma] Resisting Dirt Pickup for Roof Coatings

    Needs | Expertise
    ICL Innovation, a technology incubator for the ICL group, seeks novel material solutions to resist dirt pickup for roof coatings.
    0/5, 0 ratings
  19. Increase Available Phosphorous in Acidic and Alkaline Soils

    Needs | Expertise
    ICL Innovation, a technology incubator for ICL, is seeking an additive to standard phosphate containing fertilizers such as granular mono-ammonium phosphate (MAP), granular nitrogen phosphorous potassium (NPK), and di-ammonium phosphate (DAP) to significantly increase phosphate availability to plant roots when applied to acidic (pH 4-5) and alkaline (pH 7.5-8.5) soils.
    0/5, 0 ratings
  20. [NineSigma] Oral Delivery of Protein/Peptide Based Therapeutics

    Requests | RFPs
    NineSigma, representing a Global Pharmaceutical Corporation, invites proposals describing technologies that enable the oral delivery of protein and peptide therapeutics.
    0/5, 0 ratings
  21. [NineSigma] Self-Aggregating Drug Delivery Particles

    Requests | RFPs
    NineSigma, representing a Global Pharmaceutical Corporation, invites proposals describing drug delivery particles able to self-aggregate after injection.
    0/5, 0 ratings
  22. [NineSigma] Breakthrough Technology for Coal Ash Utilization

    Requests | RFPs
    NineSigma, representing a leading energy company, seeks a breakthrough technology for effective utilization of huge amounts of coal ash, generated from coal-fired power plant boilers.
    0/5, 0 ratings
  23. [NineSigma] Reducing CO2 Levels in Large Scale Stirred Bioreactors

    Requests | RFPs
    NineSigma, representing a global pharmaceutical company, seeks approaches to reduce the dissolved CO2 levels in existing stirred bioreactors that make minimal modifications to the bioreactor and do not increase O2 content.
    0/5, 0 ratings
  24. [NineSigma] Real-time monitoring of oxygen partial pressure in biological fluid

    Requests | RFPs
    NineSigma, representing a leading medical equipment manufacturer, seeks a small measuring device for real time monitoring of partial pressure of oxygen in biological fluid other than blood. We also welcome proposals for application of oxygen partial pressure measurement techniques used in non-medical fields to medical application.
    0/5, 0 ratings
  25. [NineSigma] Technology to Stabilize Chemical Compound in Aqueous Solution

    Requests | RFPs
    NineSigma, representing a pharmaceutical company, seeks a technology to stabilize chemical compound (landiolol hydrochloride, molecular weight: 546.05) formulated as an injectable drug in aqueous solution and then to maintain the drug activity for an extended period of time.
    0/5, 0 ratings
  26. [NineSigma] Detecting Gels in High-Viscosity Polymer Solutions

    Requests | RFPs
    NineSigma, representing a specialty materials manufacturer, invites proposals for rapid methods to detect the presence of gels during dissolution of polymers in solvent.
    0/5, 0 ratings
  27. [NineSigma] Augmented Reality System to Enhance Maintenance Technician Efficiency

    Requests | RFPs
    NineSigma, representing a building system manufacturer, invites proposals for augmented reality systems that permit maintenance personnel to have ready access to appropriate component data to enable efficient service delivery.
    0/5, 0 ratings
  28. [NineSigma] System to Permit Object Geolocation

    Requests | RFPs
    NineSigma, representing global component manufacturer, invites proposals for technology to report the location of objects in space.
    0/5, 0 ratings
  29. [IdeaConnection] Hypoxia Detection Challenge

    Challenges | Contests
    Pilots rely heavily on training to detect hypoxia symptoms. But studies show that approximately 20% of hypoxia episodes go undetected. Therefore training based detection is recommended but definitely insufficient.
    0/5, 0 ratings
  30. [IdeaConnection] To Produce a Vaccine against Piscirickettsiosis Salmonis of Coho Salmon Challenge]

    Challenges | Contests
    Piscirickettsiosis or Salmon Rickettsial Syndrome (SRS) disease is considered to be one of the most important diseases that affect the Chilean salmon farming industry, with economic losses of over US$100 million in some years. This disease was first reported, from Chile, in 1989 and is considered to be the cause of death of an estimated 1.5 million Coho salmon. This disease was also found to occur
    0/5, 0 ratings
  31. [IdeaConnection] Automobile Exhaust Pollution Challenge]

    Challenges | Contests
    A car's internal combustion engine produces exhaust when gasoline is burnt. The exhaust is mainly comprised of gases like nitrogen oxides (NOx), carbon monoxide (CO), particulate matter (PM), volatile organic compounds (VOCs) and smaller amounts of other pollutants such as sulphur dioxide (SO2) and ammonia (NH3). If present in large amounts in air, which is very likely to happen in crowded cities,
    0/5, 0 ratings
  32. [IdeaConnection] Early Pancreatic Cancer Detection Kit Challenge

    Challenges | Contests
    The disease occurs most often in the developed world, where about 70% of the new cases in 2012 originated. Pancreatic adenocarcinoma, which accounts for 95% of pancreactic cancers have a very poor prognosis: after diagnosis, 25% of people survive one year and 5% live for five years, because most are diagnosed in the late stages. There are no early detection tests for pancreatic cancers.
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    Reward:
    Teams Working